Treatment of Age-Related Macular Degeneration With Anecortave Acetate
Completed · Phase 2
Conditions studied: Macular Degeneration
In brief
The purpose of this study is to provide compassionate use of anecortave acetate sterile suspension of 15 mg for a series of five patients as a means to control classic neovascularization following failure of treatment with photodynamic therapy using Visudyne.
Key facts
- Study ID
- NCT00211458
- Run by
- Manhattan Eye, Ear & Throat Hospital
- Starts
- 2005-09-01
- Expected to finish
- 2007-09-01
- Last updated by the study team
- 2012-10-25
Who can join
Age: 50 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Clinical diagnosis of patients that previously had a failure of treatment with photodynamic therapy using Visudyne.
- Patients must be at least 50 years of age.
- Visual acuity of 20/30 to 20/320 in study eye on the Early Treatment of Diabetic Retinopathy Study (ETDRS) visual acuity chart
- Visual acuity of 20/800 or better in fellow eye on the ETDRS visual acuity chart
You may not qualify if…
- Patient with significantly compromised visual acuity in the study eye due to concomitant ocular conditions.
- Patients who have undergone intraocular surgery within the last 2 months.
- Patient participating in any other investigational drug study.
- Use of an investigational drug or treatment related or unrelated to their condition within 30 days prior to receipt of study medication.
- Inability to obtain photographs to document choroidal neovascularization (CNV) (including difficulty with venous access).
- Patient with significant liver disease or uremia.
- Patient with known adverse reaction to fluorescein and indocyanine green or iodine.
- Patient has a history of any medical condition which would preclude scheduled visits or completion of study
- Patient has had insertion of scleral buckle in the study eye
- Patient has received radiation treatment
- Patient is on anticoagulant therapy with the exception of aspirin
- Patient is pregnant or nursing.
Where it is running
- Manhattan Eye, Ear & Throat Hospital — New York, New York, United States
Full record on ClinicalTrials.gov
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