Study of Patients With Acute Renal Failure on CVVH

Completed

Conditions studied: Renal Failure

In brief

Acute kidney failure is common in children in the Pediatric Intensive Care Unit (PICU). You are being asked to participate in this study because your child is being treated for kidney failure with continuous veno-venous hemofiltration (CVVH). CVVH is a continuous, gentle form of removing excess fluids and small wastes from the blood, similar to kidney dialysis (artificial kidney). It is an accepted therapy for temporary support of kidney failure. In some patients with acute kidney failure, beginning CVVH is followed by a temporary decrease of urine output. The reason why this happens is currently unknown. The purpose of this study is to determine why this happens.

Key facts

Study ID

NCT00207909

Run by

Children's Healthcare of Atlanta

People needed

39

Starts

2005-02-01

Expected to finish

2010-03-01

Last updated by the study team

2016-06-14

Who can join

Age: 0 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The general goal of patient selection is to enroll all children for whom CVVH is instituted.
• Inclusion criteria:
• Age
• 6 months -18 years old
• Patients less than 6 months of age on ECMO (addendum #1)
• Indication for CVVH: including, but not limited to :
• Acute Renal Failure
• Oliguria
• Anuria
• Hyperkalemia
• Severe acidemia
• Azotemia
• Pulmonary Edema
• Uremic complications
• Severe electrolyte abnormalities
• Drug overdose with a filterable toxin
• Anasarca
• Rhabdomyolysis

You may not qualify if…

• Age
• Less than 6 months old (unless on ECMO)
• Greater than 18 years old Weight
• Less than 5 kilograms (unless ON ECMO) Location
• Cardiac Intensive Care Unit
• Neonatal Intensive Care Unit
• Non-adherence:
• Inability or unwillingness of the legal guardian to provide consent or inability or unwillingness of the child to provide assent

Where it is running

• Children's Healthcare of Atlanta at Egleston — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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