BRAIN (Biomarker Rapid Assessment of Ischemic iNjury)

Completed

Conditions studied: Stroke, Stroke Mimic(Conditions Presenting With Stroke-like Conditions)

In brief

This project is designed to evaluate the clinical utility of a novel blood test, the Triage Stroke Panel, as an aid in the diagnosis and assessment of stroke. The Triage Stroke Panel test device, used with the Triage MeterPlus, is a rapid, point-of-care immunoassay. The test measures the concentration of various analytes present in EDTA-anticoagulated whole blood or plasma, specifically B-type natriuretic peptide (BNP), fibrin degradation products containing D-Dimer, matrix metalloproteiase-9 (MMP-9), and S-100B. The test utilizes a proprietary algorithm for the automatic calculation of a single Multimarker Index (MMX) result from the individual biomarker values. The MMX result is being evaluated for use as an aid in the assessment and diagnosis of stroke.

Key facts

Study ID

NCT00206908

Run by

Abbott RDx Cardiometabolic

People needed

900

Starts

2002-07-01

Last updated by the study team

2015-07-22

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 and above Cerebral ischemia or intracranial hemorrhage suspected Enrollment within 24 hrs from symptom onset or last well-known time

You may not qualify if…

• None

Where it is running

• Alabama Neurological Institute — Birmingham, Alabama, United States
• University of California, Los Angeles Medical Center — Los Angeles, California, United States
• Denver Health — Denver, Colorado, United States
• University of Colorado Health Science Center — Denver, Colorado, United States
• Hartford Hospital — Hartford, Connecticut, United States
• OSF Saint Francis Medical Center — Peoria, Illinois, United States
• Kentucky Neuroscience Research — Louisville, Kentucky, United States
• University of Massachusettes, Worcester Medical Center — Worcester, Massachusetts, United States
• Henry Ford Health System — Detroit, Michigan, United States
• Ingham Regional Medical Center — Lansing, Michigan, United States
• Henepin County Medical Center — Minneapolis, Minnesota, United States
• St. Luke's Health System — Kansas City, Missouri, United States
• Duke University Hopsital — Durham, North Carolina, United States
• University of Cincinnati — Cincinnati, Ohio, United States
• Cleveland Clinic Foundation — Cleveland, Ohio, United States
• Hospital at the University of Pennsylvania — Philadelphia, Pennsylvania, United States
• University of Pittsburgh — Pittsburgh, Pennsylvania, United States
• Sentara Norfolk General Hospital — Norfolk, Virginia, United States
• Toronto Western Hospital — Toronto, Ontario, Canada
• Neurologische Universitatsklinik/Heidelberg — Heidelberg, Germany
• CHUV-Lausanne — Lausanne, Switzerland
• University of Nottingham — Nottingham, United Kingdom

Full record on ClinicalTrials.gov

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