Effects of DHEA and Exercise in the Elderly

Completed · Phase 3

Conditions studied: Healthy Volunteers

In brief

DHEA or dehydroepiandrosterone is a naturally occurring hormone secreted by tghe adrenal galnds. The secretion of HDEA declines with aging. DHEA is considered a food supplement and it is not regulated by the FDA. The purpose of this research is to evaluate ceratin of the biological effects of a reaplcement dose of DHEA. As you get older, DHEA levels are lower than you were younger. The replamcent dose is the dose of DHEA that will raise DHEA levesl to the levels found in young people. Anotehr purpose is to determine whether DHEA enhances the adaptations to an exercise training program.

Key facts

Study ID

NCT00205686

Run by

Washington University School of Medicine

People needed

64

Starts

2001-04-01

Expected to finish

2005-09-01

Last updated by the study team

2006-01-06

Who can join

Age: 65 and older, up to 78. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 65 to 78 years old men and women

You may not qualify if…

• hormone therapy, history of hormone-dependent neoplasia, PSA above 2.6 ng/mL, or active serious illness, contraindications to exercise, dementia

Where it is running

• Washington University School of Medicine — St Louis, Missouri, United States

Full record on ClinicalTrials.gov

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