Does Caffeine Affect the Sensitivity of Adenosine Perfusion Scans?

Completed · Not applicable

Conditions studied: Coronary Artery Disease

In brief

We are studying the affect of caffeine on the sensitivity of detecting coronary artery disease (blockages in the blood flow to the heart) with adenosine tracer scans. Adenosine is a drug used routinely in patients to relax heart blood vessels in order to assess for the presence of coronary artery disease. Often, if patients have had caffeine, the adenosine scan is not used because of the belief that caffeine may reduce the ability to detect coronary artery disease. We would like to test whether caffeine affects our ability to detect coronary artery disease with adenosine tracer scanning. We will perform an imaging study of the heart with adenosine after you have received caffeine.

Key facts

Study ID

NCT00205166

Run by

University of Wisconsin, Madison

People needed

50

Starts

1999-06-01

Expected to finish

2004-12-01

Last updated by the study team

2012-10-29

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients who have already completed rest/stress 99mTc sestamibi or 99mTc tetrofosmin imaging will be given a form describing this protocol and asked to volunteer for the additional scan

You may not qualify if…

• history of asthma, bronchospastic COPD, or renal failure

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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