Heart and Blood Pressure Study: The Effect of Aortic Impedance on Myocardial Relaxation

Completed · Not applicable

Conditions studied: High Blood Pressure

In brief

Does dilation of blood vessels (vasodilation), which decreases aortic stiffness, have a greater effect on heart myocardium relaxation (diastole) than vasodilation which affects mean pressure equally without improving aortic stiffness?

Key facts

Study ID

NCT00204984

Run by

University of Wisconsin, Madison

People needed

17

Starts

2005-05-01

Expected to finish

2006-12-20

Last updated by the study team

2019-02-08

Who can join

Age: 65 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects over the age of 65

You may not qualify if…

• Have known or suspected coronary artery disease
• Have known or suspected left ventricular dysfunction
• Have significant valvular, infiltrative, pericardial, or congenital heart disease
• Have a resting systolic blood pressure < 100 mmHg
• Have had an adverse reaction to nesiritide or hydralazine
• Have a serum creatinine > 2 mg/dl at Visit 1

Where it is running

• University of Wisconsin Hospital & Clinics — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.