Enteral Glutamine in Neurologically-injured Patients
Completed · Phase 4 · Has a placebo group
Conditions studied: Neurologic Injury, Traumatic Brain Injury
In brief
Nutrition is an important part of the recovery process after having a head injury so that subjects can gain strength and fight off infection. Liquid nutrition formulas are often given to patients through a tube that has been placed into the intestines for feeding when they are unable to eat on their own. Some reports suggest that nutrition with extra amounts of the amino acid called glutamine may decrease infections and hospital stay in severely injured patients.The purpose of this study is to evaluate if giving extra amounts of an amino acid called glutamine with liquid nutrition formulas will decrease the risk of infection and length of stay in the intensive care unit after having a head injury.
Key facts
- Study ID
- NCT00204971
- Run by
- University of Wisconsin, Madison
- People needed
- 102
- Starts
- 2003-01-01
- Expected to finish
- 2008-01-01
- Last updated by the study team
- 2015-10-01
Who can join
Age: 18 and older, up to 75. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Males
- Nonpregnant females
- Aged 18-75 years old
- Glasgow Coma Scores of 3-12
- Injury Severity Scores greater than or equal to 20
- Requiring enteral nutrition for a minimum of 5 days
You may not qualify if…
- Documented hepatic dysfunction
- Acute renal failure (creatinine clearance < 15 mL/min)
- Gastrointestinal malabsorptive disorder
- Infection at time of admission
Where it is running
- University of Wisconsin — Madison, Wisconsin, United States
Full record on ClinicalTrials.gov
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