Effects of CLA Supplements on Body Weight and Fat Oxidation

Completed · Phase 2 · Has a placebo group

Conditions studied: Obesity

In brief

Conjugated linoleic acid (CLA) is form of fat found in dairy foods, beef and other natural sources. When given to small animals, decreases of body fat have been noted.. Although weight loss is the best treatment for overweight and obesity, it is difficult to maintain the loss in the long term. Because of this, treatment emphasis has turned to small weight losses obtained through non-restrictive diets and prevention of weight regain. This is a study to determine if 6 months of consumption a purified form of CLA will result in greater loss of body fat than control and to determine whether CLA consumption increases total fat oxidation, which would help explain why the weight loss occurs.

Key facts

Study ID

NCT00204932

Run by

University of Wisconsin, Madison

People needed

53

Starts

2004-07-01

Expected to finish

2005-03-01

Last updated by the study team

2018-07-17

Who can join

Age: 18 and older, up to 44. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• BMI 25-29.9 kg/m2
• Absence of a weight change of greater than 3 kg in the previous 6 months

You may not qualify if…

• Presence of a physical limitation to walking exercise
• Current or recent (6 months) enrollment in a commercial or self-prescribed weight loss program
• A history of metabolic disease-ie. renal, endocrine, hepatic or gastrointestinal disease that would impact the outcome of the study
• A history of a psychiatric or eating disorders Ÿ Presence of metal implants that would interfere with body composition analysis
• Fasting plasma cholesterol >300mg/dl or triglycerides above 500 mg/dl.
• Abnormal EKG

Where it is running

• University of Wisconsin — Madison, Wisconsin, United States

Full record on ClinicalTrials.gov

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