Laryngopharyngeal Reflux and Proton Pump Inhibitor (PPI) Treatment

Completed · Phase 2/Phase 3

Conditions studied: Laryngopharyngeal Reflux

In brief

This study proposes to investigate prospectively, the presence of molecular markers for inflammation in laryngopharyngeal reflux (LPR) patients and to study the effect of a proton pump inhibitor (Aciphex) on these molecular markers. The investigators will be evaluating a group of patients before and after treatment. This group will be patients that have untreated laryngopharyngeal reflux diagnosed by laryngoscopic assessment and a 24-hour probe.

Key facts

Study ID

NCT00204698

Run by

University of Utah

People needed

24

Starts

2003-08-01

Expected to finish

2006-05-01

Last updated by the study team

2008-01-16

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• The subject group will consist of 25 subjects who have untreated LPR diagnosed by laryngoscopic assessment and 24-hour pH probe.

Where it is running

• University of Utah — Salt Lake City, Utah, United States

Full record on ClinicalTrials.gov

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