Study of Fluid Collection of the Chest in Children With Pneumonia

Completed · Phase 3

Conditions studied: Community Acquired Bacterial Pneumonia, Paraneumonic Effusion

In brief

The purpose of this study is to determine the best treatment for children with a fluid collection in the chest associated with an underlying pneumonia. Researchers generally agree that a child with a large fluid collection in the chest need to have the fluid drained in addition to anitbiotics. There have been many treatments studied in children that have been shown to be effective and safe, but the treatments have never been compared to each other in a randomized controlled study. The optimal treatment of pediatric parapneumonic effusions remains controversial. The objective of this study is to compare the use of conventional management (antibiotics with thoracostomy tube placement) with primary thorascopic drainage (see protocol). Our hypothesis is that pediatric patients with parapneumonic effusion, regardless of pleural fluid composition and loculations, have decreased morbidity when treated with early thoroscopic adhesiolysis (VATS) compared with conservative treatment.

Key facts

Study ID

NCT00202826

Run by

Corewell Health West

People needed

30

Starts

2003-11-01

Expected to finish

2004-03-01

Last updated by the study team

2021-12-06

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• consecutive pediatric patients with a bacterial pneumonia and parapneumonic effusion
• community acquired disease
• children age 0 to 18 years

You may not qualify if…

• hospital acquired pneumonia
• thoracentesis or chest tube drainage outside hospital
• patients with incorrected cardiac disease

Where it is running

• DeVos Children's Hospital — Grand Rapids, Michigan, United States

Full record on ClinicalTrials.gov

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