Evaluation of Vitrase as a Spreading Agent

Completed · Phase 3

Conditions studied: Pain

In brief

The purpose of this study is to determine whether Vitrase (hyaluronidase for injection) is effective as a spreading agent for other injected drugs prior to ocular surgery

Key facts

Study ID

NCT00198484

Run by

Bausch & Lomb Incorporated

People needed

108

Starts

2004-10-01

Expected to finish

2005-02-01

Last updated by the study team

2013-03-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Scheduled for an ophthalmic surgical procedure

You may not qualify if…

• Documented history of hypersensitivity to hyaluronidase or any other ingredient in Vitrase
• Known history of hypersensitivity reaction to bee or wasp venom
• Needing enhanced absorption and dispersion of dopamine, alpha agonist drugs, furosemide, the benzodiazepines, or phenytoin
• Inflammation or apparent clinical signs of infection in the area where Vitrase was to be injected

Where it is running

• David Wirta, MD, Inc. — Newport Beach, California, United States
• Richard A Lewis, MD — Sacramento, California, United States
• E Randy Craven, MD — Littleton, Colorado, United States
• The Eye Care Group — New Haven, Connecticut, United States
• Advanced Eye Care, PC — Fort Oglethorpe, Georgia, United States
• Donald E Beahm, MD — Great Bend, Kansas, United States
• Cincinnati Eye Institute NKY — Edgewood, Kentucky, United States
• Cornea Consultants — Boston, Massachusetts, United States
• Hunkeler Eye Institute — Kansas City, Missouri, United States
• Ophthalmic Consultants of Long Island — Rockville Centre, New York, United States
• David L Schwartz, MD — Tulsa, Oklahoma, United States
• Black Hills Regional Eye Institute — Rapid City, South Dakota, United States
• Texan Eye Care PA — Austin, Texas, United States
• Ophthalmology Service, Brooke Army Medical Center — Fort Sam Houston, Texas, United States
• Ophthalmology Visual Science — Galveston, Texas, United States
• Houston Eye Associates — Houston, Texas, United States
• David G Shulman, MD — San Antonio, Texas, United States
• Central Texas Eye Center — San Marcos, Texas, United States

Full record on ClinicalTrials.gov

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