Cascade PRFM Study: The Evaluation of Cascade Platelet-Rich Fibrin Matrix (PRFM) on Rotator Cuff Healing

Withdrawn before enrolling · Phase 3

Conditions studied: Rotator Cuff, Tendon Injuries

In brief

Hypothesis: The use of cascade platelet-rich fibrin matrix (PRFM) on medium and large sized rotator cuff tears will improve patient results versus the control results by 50%. The purpose of this study is to examine the effect of PRFM on rotator cuff repairs. Since locally applied platelet-derived growth factor (PDGF) has shown early promise in enhancing tendon and ligament healing in anterior cruciate ligament (ACL) and medial collateral ligament (MCL) reconstruction, the investigators believe that locally applied PRFM will enhance the quality of rotator cuff repairs.

Key facts

Study ID

NCT00198185

Run by

Hospital for Special Surgery, New York

People needed

0

Starts

2005-01-01

Expected to finish

2005-01-01

Last updated by the study team

2018-01-04

Who can join

Age: 45 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Patients 45 years of age and older who have failed conservative treatment for rotator cuff pathology.
• Patients in this study will have full thickness rotator cuff tears that are classified arthroscopically as medium (1 to 3 cm) or large (3 to 5 cm) and that are treated with arthroscopic repair.

You may not qualify if…

• Patients who have undergone revision procedures, mini-open, or open procedures will be excluded.

Where it is running

• Hospital for Special Surgery — New York, New York, United States

Full record on ClinicalTrials.gov

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