Ifosfamide/Carboplatin/Etoposide/Rituxan Followed by Zevalin in Relapsed/Refractory Intermediate Grade B-Cell Lymphoma
Completed · Phase 2
Conditions studied: Non-Hodgkins Lymphoma
In brief
In this Multicenter trial, we will evaluate the feasibility, toxicity, and efficacy of treatment with 90Y Zevalin following a short course of salvage chemotherapy in patients with relapsed/refractory intermediate grade B-cell non-Hodgkin's lymphoma.
Key facts
- Study ID
- NCT00193505
- Run by
- SCRI Development Innovations, LLC
- People needed
- 40
- Starts
- 2003-10-01
- Expected to finish
- 2005-08-01
- Last updated by the study team
- 2011-05-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- To be included in this study, you must meet the following criteria:
- Intermediate grade CD20-positive B-cell non-Hodgkin's lymphoma
- Persistent lymphoma after one or two previous chemotherapy regimens
- Patients should not be considered candidates for high-dose chemotherapy
- Ability to perform activities of daily living with assistance
- Measurable or evaluable disease
- Age > 18 years
- Adequate bone marrow, liver and kidney function
You may not qualify if…
- You cannot participate in this study if any of the following apply to you:
- Patients with impaired bone marrow reserve
- Female patients who are pregnant or lactating
- Serious active infection at the time of treatment
- Any other serious underlying condition
- Brain or meningeal) with lymphoma
- HIV or AIDS-related lymphoma
- Received external beam radiation therapy to > 25% of active bone marrow.
- History of other cancers, either active or treated
- Please note: There are additional inclusion/exclusion criteria. The study center will determine if you meet all of the criteria. If you do not qualify for the trial, study personnel will explain the reasons. If you do qualify, study personnel will explain the trial in detail and answer any questions you may have.
Where it is running
- Tennessee Oncology, PLLC — Nashville, Tennessee, United States
Full record on ClinicalTrials.gov
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