ResQ Trial: Impact of an ITD and Active Compression Decompression CPR on Survival From Out-of-Hospital Cardiac Arrest

Stopped early · Not applicable

Conditions studied: Heart Arrest, Death, Sudden, Cardiac, Cardiopulmonary Resuscitation, Cardiac Arrest

In brief

The purpose of this study is to determine whether performing active compression decompression cardiopulmonary resuscitation (ACD-CPR) with an impedance threshold device (ITD) compared to conventional standard cardiopulmonary resuscitation (S-CPR) will impact the neurologic recovery and survival to hospital discharge following out-of-hospital cardiac arrest.

Key facts

Study ID

NCT00189423

Run by

Advanced Circulatory Systems

People needed

1653

Starts

2005-10-01

Expected to finish

2010-07-01

Last updated by the study team

2017-12-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adult subjects initially presumed or known to be 18 years of age or older
• Subjects who present with out-of-hospital cardiac arrest from presumed cardiac etiology and who receive CPR by Emergency Medical Services (EMS) personnel for at least 1 minute
• Subjects whose airways are managed with a cuffed ET tube, combitube, or laryngeal mask airway or facemask

You may not qualify if…

• Adult subjects presumed or known to be less than 18 years of age
• Subjects with known or likely traumatic injuries causing cardiac arrest or cardiac arrest of presumed noncardiac origin
• Subjects with preexisting Do Not Resuscitate (DNR) orders
• Subjects with signs of obvious clinical death or conditions that preclude the use of CPR
• Family or legal representative request that the subject not be entered into the study
• Subjects experiencing in-hospital cardiac arrest
• Subjects with a recent sternotomy with wound not appearing completely healed (if unknown) or less than 6 months (if known)
• Subjects who received less than 1 minute of CPR by EMS personnel
• Subjects with a complete airway obstruction that cannot be cleared or in whom attempts at advanced airway management are unsuccessful
• Subjects intubated with a leaky or uncuffed advanced airway device or presence of stomas, tracheotomies, or tracheostomies
• Subjects who rearrest and are encountered by EMS within 365 days of the index cardiac arrest

Where it is running

• Site 07: Indianapolis, IN — Indianapolis, Indiana, United States
• Site 06: Washtenaw & Livingston Counties, MI — Ann Arbor, Michigan, United States
• Site 04: Oakland & Macomb Counties, MI — Royal Oak, Michigan, United States
• Site 02: Minneapolis, MN — Minneapolis, Minnesota, United States
• Site 01: St. Paul, MN — Saint Paul, Minnesota, United States
• Site 03: Whatcom County, WA — Bellingham, Washington, United States
• Site 05: Oshkosh, WI — Oshkosh, Wisconsin, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.