Study for Treatment of Cancer in Children With Ataxia-telangiectasia

Completed · Not applicable

Conditions studied: Ataxia-Telangiectasia

In brief

This is a pilot/feasibility study designed to investigate the feasibility of treating children with Ataxia-Telangiectasia (A-T) and cancer with regimens nearly as intense as non-A-T patients with cancer would receive.

Key facts

Study ID

NCT00187057

Run by

St. Jude Children's Research Hospital

People needed

6

Starts

2002-09-01

Expected to finish

2013-06-01

Last updated by the study team

2015-08-27

Who can join

Age: any, up to 10. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patient must have a diagnosis of Ataxia-Telangiectasia (A-T).
• Patient must have a diagnosis of either acute lymphoblastic leukemia (ALL) or lymphoma (non-Hodgkin lymphoma or Hodgkin's disease).
• Patients with other malignancies (solid tumors, rare malignancies, or relapsed hematopoietic malignancies) will be eligible for the biologic studies of this protocol; they will receive best clinical management chemotherapy.
• Patients do not have to be previously untreated. If prior chemotherapy has already started (up through induction), therapy will be continued according to protocol at a clinically appropriate time point.

You may not qualify if…

• Patients who do not have a diagnosis of Ataxia Telangiectasia (A-T).

Where it is running

• St. Jude Children's Research Hospital — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

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