Therapy for Children With Advanced Stage High Risk Neuroblastoma

Completed · Phase 2

Conditions studied: Neuroblastoma

In brief

This is a Phase II pilot study of chemotherapy and surgery for children with advanced stage high-risk neuroblastoma utilizing topotecan during an upfront window and other active agents during induction and intensification phases. The primary purpose is to estimate the response rate to an upfront window of two cycles of intravenous topotecan. We hypothesize that the topotecan window will be an effective therapy in terms of the response rate.

Key facts

Study ID

NCT00186849

Run by

St. Jude Children's Research Hospital

People needed

30

Starts

1997-10-01

Expected to finish

2001-04-01

Last updated by the study team

2009-05-20

Who can join

Age: any, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Advanced stage,high-risk neuroblastoma
• Histologic proof of neuroblastoma
• Adequate renal function
• ECOG performance status 0-2

You may not qualify if…

• Previous therapy

Where it is running

• St. Jude Children's Research Hospital — Memphis, Tennessee, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.