A Human In-vivo Model for the Detection of Inflammatory and Nociceptive Biomarkers

Completed · Not applicable

Conditions studied: Skin Diseases

In brief

This study aims to establish a novel approach assisting the rational development of analgesic and anti-inflammatory drugs. In a first step we will test in healthy human volunteers whether proteins mediating inflammation and pain can be detected in an experimentally induced inflammatory skin lesion. Fluids that will be used to detect such proteins will be collected from the inflamed skin site via small porous catheters. We wish to establish the expression pattern of different proteins and correlate it with various tests assessing pain.

Key facts

Study ID

NCT00186563

Run by

Martin Angst

People needed

13

Last updated by the study team

2013-06-19

Who can join

Age: 21 and older, up to 60. Sex: any. Healthy volunteers: accepted.

Where it is running

• Stanford University School of Medicine — Stanford, California, United States

Full record on ClinicalTrials.gov

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