Reducing Risk and Trauma-Related Stress in Persons Living With HIV
Stopped early · Phase 1/Phase 2
Conditions studied: HIV, PTSD
In brief
This two-year study tested the concept that an intervention, which reduces trauma-related symptoms among adults who are living with human immunodeficiency virus (HIV), are experiencing trauma-related stress symptoms, and engaging in behavior that facilitates HIV transmission, can reduce the transmission risk of (HIV). Our central premise was that by first treating trauma symptoms, we would enhance the effects of a skills-building HIV risk reduction intervention for adults experiencing trauma-related symptoms such as hyperarousal, dissociation, and avoidance. The study aims were to: 1. To determine if decreasing trauma-related stress symptoms improves HIV risk reduction behavior above a standard HIV risk reduction intervention alone post-intervention and 3 months after the small group intervention sessions; 2. To determine whether key variables moderate the intervention's effects. For instance, gender, age, ethnicity, or psychological distress (e.g., depression, anxiety) may interact with the intervention to affect risky sexual or drug-related behavior; and 3. To determine whether there is evidence that the theoretical mediator variables, which include trauma-related stress symptoms, self-efficacy, communication skills, and social support mediate the intervention's effects on outcomes. This information addresses the theoretical question of why the intervention works.
Key facts
- Study ID
- NCT00186030
- Run by
- Stanford University
- People needed
- 102
- Starts
- 2003-04-01
- Expected to finish
- 2004-03-01
- Last updated by the study team
- 2006-10-06
Who can join
Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- must be 18 years or older, must be HIV-positive
- report engaging in behavior that could put them at risk for HIV transmission during the past 3 months
- report experiencing one or more trauma-related symptoms (i.e., reexperiencing, hyperarousal, or avoidance) occurring within the past three months.
You may not qualify if…
- experience psychological symptoms or substance use problems so severe that it would impair their ability or the ability of others to participate in a group intervention
Where it is running
- Center for AIDS Intervention Research (CAIR) — Milwaukee, Wisconsin, United States
Full record on ClinicalTrials.gov
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