Chest Wall Oscillation for Asthma and COPD Exacerbations Trial (COAT)

Completed · Not applicable · Has a placebo group

Conditions studied: Asthma, Chronic Obstructive Pulmonary Disease (COPD), Undifferentiated Asthma/COPD

In brief

The objective of this study was to evaluate the use of high frequency chest wall oscillation (HFCWO) early in the treatment of adults hospitalized for acute asthma or chronic obstructive pulmonary disease (COPD).

Key facts

Study ID

NCT00181285

Run by

University of Chicago

People needed

52

Starts

2003-10-01

Expected to finish

2008-05-01

Last updated by the study team

2018-08-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Age 18 years and older
• Admission to the inpatient medical service
• Physician-diagnosed asthma or asthma/COPD or COPD exacerbation.
• Evidence of airflow obstruction on spirometry

You may not qualify if…

• More than 24 hours since admission to the inpatient medical service
• Admission to an intensive care unit
• Hospital discharge planned within the next 24 hours
• Other chronic respiratory disease (e.g., sarcoidosis, idiopathic pulmonary fibrosis)
• Chest wall abnormalities (e.g., severe kyphoscoliosis) that precludes using the vest
• Chest wall or abdominal trauma/surgery in the past 6 weeks that precludes using the vest
• Physician declines to provide consent
• Patient unable (e.g., history of cognitive impairment, unable to understand English) or declines to provide consent
• Previous participant in this study
• Corticosteroid therapy (prednisone >0 mg/d equivalent) for >1 week prior to admission

Where it is running

• Mercy Hospital and Medical Center — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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