Airway Clearance for Prevention of Chronic Obstructive Pulmonary Disease (COPD) Exacerbation

Completed · Phase 4 · Has a placebo group

Conditions studied: COPD, Chronic Bronchitis, Emphysema

In brief

The purpose of this study is to show that one form of mechanical airway clearance techniques, High Frequency Chest Wall Oscillation (HFCWO)using a pneumatic vest, will diminish exacerbations of COPD which will improve respiratory health status.

Key facts

Study ID

NCT00181207

Run by

Johns Hopkins University

People needed

50

Starts

2004-05-01

Expected to finish

2007-12-01

Last updated by the study team

2018-10-19

Who can join

Age: 45 and older, up to 85. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Physician Diagnosis of COPD,chronic bronchitis and/or emphysema
• Forced Expiratory Volume in 1 second (FEV1)/ Forced Vital Capacity (FVC) < or = 70%
• FEV1 < or = 65%
• Current or former smoker > or = 20 pack years
• History of 1 or more COPD exacerbations in past 6 months necessitation hospitalization, Emergency Department (ED) visit, antibiotic or steroid prescription

You may not qualify if…

• Other lung diseases
• Co-morbid illnesses such as cancer, liver disease, cardiomyopathy
• Recent chest wall or abdominal trauma or surgery that would preclude using the vest

Where it is running

• Johns Hopkins Asthma and Allergy Center — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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