Molecular Processes of the Relaxation Response in Older Adults

Completed · Phase 2

Conditions studied: Stress

In brief

The purpose of this study is to examine the molecular (nitric oxide) and biochemical (epinephrine, norepinephrine, cortisol and ACTH) parameters that are associated with RR elicitation and which may counteract the effects of acute stress in the elderly.

Key facts

Study ID

NCT00179569

Run by

Beth Israel Deaconess Medical Center

People needed

40

Starts

2005-08-01

Expected to finish

2007-09-01

Last updated by the study team

2007-11-05

Who can join

Age: 60 and older, up to 80. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• 60-80 years of age
• healthy individuals
• willing and able to attend treatment sessions
• willing to learn how to do and practice the relaxation-response
• access to a working telephone
• read and write English

You may not qualify if…

• Major medical or psychiatric illness
• asthma or seasonal allergies (resulting in nitric oxide levels >60 ppb)
• smoking
• previous relaxation-response practice
• current use of the following medications:systemic corticosteroids, anti-convulsants/psychotics, immunosuppressants, cytotoxic therapy, anabolic steroids, antidepressants (other than SSRIs), dicyclomine, bile acid binding resins, or sympathomimetic medication

Where it is running

• BIDMC — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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