Chemotherapy With Whole Body Hyperthermia to Treat Resistant Breast, Endometrial, Cervical and Ovarian Cancers

Status unconfirmed · Phase 2

Conditions studied: Breast Neoplasms, Endometrial Neoplasms, Cervix Neoplasms, Ovarian Neoplasms

In brief

Thermal therapy (hyperthermia of heat) can increase the effect of chemotherapy treatments. By itself, thermal therapy can also kill cancer cells. By using thermal therapy to treat the whole body, the investigators can treat cancer cells wherever they are throughout the entire body. In this study, the investigators are testing the combination of thermal therapy combined with chemotherapy to see: 1. if it improves the effect of the chemotherapy drugs, 2. if it helps the body fight the cancer cells, and 3. if this treatment is safe for the patient. This study does not offer heat treatment alone. Any patient with advanced or metastatic breast, or endometrial cancer resistant to standard treatment may be treated with the phase II protocol therapy; however, the patient will need to undergo some medical tests to make sure this treatment would be safe for them.

Key facts

Study ID: NCT00178802
Run by: The University of Texas Health Science Center, Houston
People needed: 24
Starts: 1996-06-01
Expected to finish: 2010-12-01
Last updated by the study team: 2010-04-23

Who can join

Age: any. Sex: female. Healthy volunteers: accepted.

You may qualify if…

Resistant breast, endometrial, cervix, or ovarian cancer
No active metastasis to the brain
No more than 8 previous regimes of Doxil
Successful completion of preliminary function tests
Good ECOG score

You may not qualify if…

Active metastasis to the brain
8 or more previous cycles of Doxil
Poor completion of preliminary function tests
Poor ECOG score

Where it is running

Memorial Hermann Hospital — Houston, Texas, United States

Full record on ClinicalTrials.gov

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