Measuring Alterations of DNA in Human Blood

Completed

Conditions studied: Neoplasms

In brief

The purpose of this research is to evaluate an automated, laser-based technique for measuring DNA damge resulting from radiation. We want to use controlled exposure on cancer patients to help develop a measurement to test people who may have been accidentally exposed to radiation.

Key facts

Study ID

NCT00178308

Run by

University of Rochester

People needed

24

Last updated by the study team

2006-09-11

Who can join

Age: 21 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Male or female, age 21 to 70 years old.
• Patient undergoing with anti-neoplastic agent(s) known to have genotoxic activity (e.g., cyclophosphamide, 5-FU, cisplatin, Ara-C.
• X-irradiation may be considered, so long as a substantial fraction of red marrow is exposed (e.g., femur or chest/trunk region);
• treatment could be ongoing therapy or initial therapy.

Where it is running

• University of Rochester — Rochester, New York, United States

Full record on ClinicalTrials.gov

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