Radiation-Induced Cytokine Cascades and Their Correlation With Central Nervous System Injury

Completed

Conditions studied: Brain Neoplasm

In brief

Treatment for brain cancer may include radiation therapy. Radiation therapy is the treatment of tumors with X-rays. This study is related to understanding the side effects of radiation treatment for brain tumors. This study is being conducted by the University of Rochester Cancer Center to compare the extent of side effects of brain cancer treatment with changes in levels of blood proteins called cytokines.

Key facts

Study ID

NCT00178295

Run by

University of Rochester

People needed

44

Starts

1999-11-01

Last updated by the study team

2015-08-05

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Any patient who will be treated to the brain or spinal axis for a CNS tum Patients so treated will be stratified according to whether or not the hypo is included in the treatment fields.
• Patients receiving external beam radiation to the brain may also be rece chemotherapy or interferon-beta. (Add. #1, 11-9-95)
• Patients receiving high dose rate (stereotactic radiosurgery) are eligible.
• Patients must sign a study specific informed consent meeting all federal a guidelines.
• Patients of any age, including children, are eligible (Add. #3, 11/25/97).

You may not qualify if…

• Patients who have a malignancy involving the hypothalamic-pituitary ax
• Patients who are not treated with irradiation to the brain or spinal axis.

Where it is running

• University of Rochester, Dept. Radiation Oncology — Rochester, New York, United States

Full record on ClinicalTrials.gov

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