Response of Topical Capsaicin in Alopecia Areata

Completed · Phase 4

Conditions studied: Alopecia Areata

In brief

It has been postulated that Alopecia Areata (AA) is, at least in part, a neurologically mediated disease. Research supporting this theory includes the finding that nerves surrounding the hair follicles are collapsed. We want to take this research a step further and show that not only are these perifollicular nerves collapsed, but that their function is also impaired.

Key facts

Study ID

NCT00176969

Run by

University of Minnesota

People needed

24

Starts

1997-08-01

Expected to finish

2000-06-01

Last updated by the study team

2014-06-02

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Must have alopecia totalis or universalis.
• Be in good health.
• Not be taking any medications including topical medications
• Be 18 years or older.
• Be willing to apply study medication or vehicle as directed, comply with instructions and commit to follow-up visits.
• Not have had hair chemically treated (including colored hair, permed hair, etc) within the month prior to the study.

You may not qualify if…

• Absence of extensive alopecia areata.
• People not in good health.
• People taking medications.
• Allergies to capsaicin.
• Presence of irritated or visibly inflamed scalp.
• Having had hair chemically treated (including colored hair, permed hair, etc.) within the month prior to study.

Where it is running

• University of Minnesota — Minneapolis, Minnesota, United States

Full record on ClinicalTrials.gov

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