Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients

Withdrawn before enrolling

Conditions studied: Low Cardiac Output

In brief

Each year in the United States more than 30,000 children are admitted to intensive care units. The majority of these children have some degree of heart instability during their stay, yet there is currently no routine way to measure the actual amount of blood that the heart pumps. The ability to measure the amount of blood that the heart pumps accurately and easily at frequent intervals would be very helpful to the doctor caring for these children because many of them have poor heart function as a result of their illnesses. Current techniques used in adults to measure output of the heart are either not readily transferred to children or demand difficult invasive procedures. Because of this, the amount of blood that the heart pumps cannot be measured with enough frequency to help guide care. Despite this reality, accurate measurements of the amount of blood that the heart pumps in these patients at crucial points in their illnesses would allow for more accurate use of potentially harmful procedures and could possibly improve the outlook for these children. Likewise, being able to correctly measure blood volume could provide a better way to estimate the pressure on the heart and improve treatment. The purpose of this research study is to compare the accuracy of doctor estimates of heart output, and establish the usefulness of central blood volume measurements by PCOM (pediatric cardiac output measurements), a less invasive procedure

Key facts

Study ID

NCT00167440

Run by

University of Rochester

People needed

0

Starts

2004-08-01

Expected to finish

2008-07-01

Last updated by the study team

2015-11-26

Who can join

Age: any, up to 16. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• patients less than 16 years of age
• admitted to the PICU after surgery
• indwelling central venous and arterial catheters
• arterial oxygen saturation greater than 94% while breathing 60% oxygen
• ability to draw blood from both arterial and venous catheters
• require fluid bolus or dose of diuretic
• require mechanical ventilation
• no change in dosing of inotropic or vasoactive agents over prior to 60 minutes

You may not qualify if…

• hemodynamic instability

Where it is running

• University of Rochester — Rochester, New York, United States

Full record on ClinicalTrials.gov

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