Treatment of Melasma With Jessner's Solution vs. Trichloroacetic Acid

Completed · Phase 4

Conditions studied: Melasma

In brief

Melasma is an acquired discoloration of the skin characterized by brown patches. Chemical peels using agents such as Jessner's solution and trichloroacetic acid (TCA) are commonly used to treat melasma. A chemical peel involves applying the peeling agent to the skin for a short period. The skin will peel similar to a sunburn, and moisturizers are applied to the skin. Although both agents are well-accepted, there have been no good comparisons of the two agents. The purpose of this study is determine if there is a difference in the effectiveness of these two agents.

Key facts

Study ID

NCT00166192

Run by

Emory University

People needed

19

Starts

2008-01-01

Expected to finish

2013-11-01

Last updated by the study team

2013-11-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Adults > 18 years old
• Clinical diagnosis of melasma
• Mental capacity to give informed consent

You may not qualify if…

• Pregnancy
• H/o allergy to Jessner's solution, tricholoracetetic acid, tretinoin, or hydroquinone
• Active dermatitis
• Presence of cutaneous infection

Where it is running

• Emory University Dermatology Clinic — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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