Endothelial Hyperpolarization in Humans

Stopped early · Phase 2

Conditions studied: Hyperlipidemia

In brief

The purpose of this study is to elucidate the role Endothelium-Derived Hyperpolarizing Factor (EDHF) plays in dilating blood vessels and whether it differs between healthy people and those with high cholesterol. A second purpose of the study is to determine the identity of EDHF.

Key facts

Study ID

NCT00166166

Run by

Emory University

People needed

174

Starts

2002-07-01

Expected to finish

2013-01-01

Last updated by the study team

2018-08-15

Who can join

Age: 21 and older, up to 65. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Hyperlipidemic (LDL > 140)
• Healthy Volunteer

You may not qualify if…

• Pregnancy
• Diabetes mellitus
• Cardiovascular Disease
• Hypertension
• Use of any regular medications
• Renal insufficiency
• Smoking (current or within the past 5 years)
• Bleeding disorder

Where it is running

• Emory University School of Medicine — Atlanta, Georgia, United States

Full record on ClinicalTrials.gov

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