Tangential Radiation Therapy Without Axillary Dissection in Breast Cancer

Completed · Phase 2

Conditions studied: Early-Stage Breast Cancer

In brief

The purpose of this study is to evaluate whether treatment to the axilla (area under the arm) can be safely minimized by omitting axillary surgery and full axillary radiation therapy and replacing it with radiation therapy to the breast and lower axilla.

Key facts

Study ID

NCT00165243

Run by

Dana-Farber Cancer Institute

People needed

100

Starts

1998-09-01

Expected to finish

2016-12-01

Last updated by the study team

2017-06-07

Who can join

Age: 55 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients must have clinical stage I or II breast cancer, clinically uninvolved axillary nodes.
• Patients must be 55 years or older.
• Patients must undergo total excision of the primary invasive tumor
• Final pathologic margin status must be negative
• Only estrogen receptor (ER) or progesterone receptor (PR) positive tumors will be permitted

You may not qualify if…

• Prior history of malignancy, except for non-melanoma skin cancers and carcinoma in situ fo the cervix

Where it is running

• Dana-Farber Cancer Institute — Boston, Massachusetts, United States
• Massachusetts General Hospital — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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