Counseling Interventions for BRCA 1/2 Cancer Susceptibility Testing

Completed · Not applicable

Conditions studied: Breast Cancer, Ovarian Cancer

In brief

To evaluate two different ways of providing information about genetic testing for BRCA1 and BRCA2 alterations. The two forms of counseling are genetic counseling and enhanced informed consent which cover similar material but are organized differently.

Key facts

Study ID

NCT00165152

Run by

Dana-Farber Cancer Institute

People needed

150

Starts

1998-07-01

Expected to finish

2005-06-01

Last updated by the study team

2012-08-09

Who can join

Age: 18 and older. Sex: female. Healthy volunteers: not accepted.

You may qualify if…

• 18 years of age or older
• Member of a family in which a BRCA1 or BRCA2 deleterious germline mutation has been identified, whether or not the individual has had cancer herself; written documentation of the family mutation must be available for laboratory purposes during the testing process.
• Personal and/or family history of breast/ovarian/other cancer consistent with BRCA 1/2 heredity with posterior probability of carrying an altered gene
• Documentation of key family member cancer diagnoses is required

You may not qualify if…

• Males, will be offered BRCA 1/2 testing through other protocols
• Individuals unable to speak or write English
• Already participated in a genetic counseling program for BRCA1 or BRCA2 testing
• Life expectancy of less than 12 months.

Where it is running

• Massachusetts General Hospital — Boston, Massachusetts, United States
• Dana-Farber Cancer Institute — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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