Abuse Potential of Buprenorphine and Naloxone in Non-Dependent Opioid Users

Completed · Not applicable

Conditions studied: Opioid-Related Disorders

In brief

Buprenorphine is a medication used to treat opioid addiction, but individuals who use this drug are at risk of abusing it. A buprenorphine and naloxone combination may reduce the likelihood of buprenorphine addiction. This study will evaluate the potential for abuse of buprenorphine and a buprenorphine and naloxone combination in non-dependent opioid users.

Key facts

Study ID

NCT00158236

Run by

National Institute on Drug Abuse (NIDA)

People needed

7

Starts

1997-01-01

Expected to finish

1998-03-01

Last updated by the study team

2017-01-12

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Current opioid abuse
• Not physically dependent on opioids

You may not qualify if…

• Significant medical or psychiatric illness (e.g., insulin-dependent diabetes or schizophrenia)
• Seeking substance abuse treatment (will be assisted with referrals to community-based treatment programs)
• Pregnant

Where it is running

• Johns Hopkins University (BPRU) Bayview Campus — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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