Restoration of Walking in Multiple Sclerosis Using Treadmill Training.

Completed · Not applicable

Conditions studied: Multiple Sclerosis

In brief

The primary purpose of this study is to collect preliminary and pilot data to begin to determine whether the use of body weight support treadmill therapy (BWSTT) with and without driven-gait-orthotics (DGO), results in improved motor recovery and ambulation MS patients with gait impairment

Key facts

Study ID

NCT00156676

Run by

US Department of Veterans Affairs

People needed

30

Starts

2004-09-01

Expected to finish

2007-09-01

Last updated by the study team

2013-09-20

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Clinical diagnosis of MS by McDonald criteria. EDSS level between 4-6.5.

You may not qualify if…

• Cardiovascular: recent MI < 4 wk, uncontrolled HTN >190/110 mmHg, Uncontrolled diabetes (blood glucose 2X above the upper limit of normal or non-fasting blood drain).
• Symptomatic fall in blood pressure (>30mm Hg), when upright in the body support apparatus, despite medical therapy.
• Circulatory problems, history of vascular claudication or pitting edema.
• Cognitive impairment MMSE < 21.
• Body weight over 150 kg (structural limits of the Lokomat).
• Lower extremity injuries that limit range of motion or function.
• Joint problems (hip or leg) that limit range of motion or cause pain with movement despite treatment.
• Unstable fractures.
• Pressure sores with any skin breakdown in areas in contact with the body harness or DGO apparatus.
• Chronic and ongoing alcohol or drug abuse.
• Pre-morbid, ongoing depression or psychosis.

Where it is running

• Providence VA Medical Center — Providence, Rhode Island, United States

Full record on ClinicalTrials.gov

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