Study Evaluating Inhibitor Specificity in Hemophilia A

Withdrawn before enrolling · Phase 4

Conditions studied: Hemophilia A

In brief

This investigation will utilize a systematic determination of anti-FVIII antibody specificity in PTPs (\> 50 ED) with hemophilia A who have developed inhibitors in response to treatment with any FVIII product(s). A group of patients with hemophilia A, who have no evidence of current or prior FVIII inhibitor will be included for comparison. The objective of this study is to describe the patterns of antibodies and associated epitopes in the study population.

Key facts

Study ID

NCT00151385

Run by

Wyeth is now a wholly owned subsidiary of Pfizer

People needed

0

Starts

2005-11-01

Expected to finish

2007-10-01

Last updated by the study team

2012-06-28

Who can join

Age: any. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• · Patients with moderate or severe congenital hemophilia A, a current FVIII inhibitor, who have taken at least two different FVIII products during their lifetime.

You may not qualify if…

• Patients who have had an inhibitor prior to their current inhibitor.
• Patients with immune disorders.

Where it is running

• Study site — Atlanta, Georgia, United States
• Study site — Detroit, Michigan, United States
• Study site — New Hyde Park, New York, United States
• Study site — New York, New York, United States
• Study site — Philadelphia, Pennsylvania, United States
• Study site — Houston, Texas, United States
• Study site — San Antonio, Texas, United States
• Study site — Brussels, Belgium
• Study site — Leuven, Belgium
• Study site — La Bouëxière, France
• Study site — Le Kremlin-Bicêtre, France
• Study site — Lyon, France
• Study site — Berlin, Germany
• Study site — Bonn, Germany
• Study site — Bremen, Germany
• Study site — München, Germany
• Study site — Münster, Germany
• Study site — Florence, Italy
• Study site — Milan, Italy
• Study site — Madrid, Spain
• Study site — Valencia, Spain
• Study site — London, United Kingdom
• Study site — Manchester, United Kingdom

Full record on ClinicalTrials.gov

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