The Efficacy and Safety of Escitalopram for Depression in Multiple Sclerosis

Stopped early · Phase 4

Conditions studied: Depression, Multiple Sclerosis

In brief

Emotionally labile, depressed participants with multiple sclerosis treated with escitalopram will have a greater reduction in emotional lability scores and in their psychological distress scores than those who are randomized to receive placebo.

Key facts

Study ID

NCT00151294

Run by

Weill Medical College of Cornell University

People needed

20

Starts

2004-11-01

Expected to finish

2006-10-01

Last updated by the study team

2006-09-14

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical diagnosis of multiple sclerosis
• Having mild to moderate depressive symptoms, with or without emotional lability
• Experiencing psychological distress

You may not qualify if…

• Meeting DSM-IV diagnostic criteria for Major Depressive Disorder or another Axis 1 diagnosis
• Cognitive impairment
• The presence of an unstable medical illness that might preclude completion of the study -

Where it is running

• NewYork Presbyterian Hospital — White Plains, New York, United States

Full record on ClinicalTrials.gov

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