Efalizumab for Eczema
Completed · Phase 2
Conditions studied: Dermatitis, Atopic
In brief
The purpose of this study is to demonstrate a measurable improvement on a validated scale in a small population of adult patients with atopic dermatitis (eczema).
Key facts
- Study ID
- NCT00146003
- Run by
- University of Medicine and Dentistry of New Jersey
- People needed
- 10
- Starts
- 2005-03-01
- Expected to finish
- 2007-12-01
- Last updated by the study team
- 2008-08-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Adults (18 years or older) with atopic dermatitis with 5% or more body surface area involvement
- Investigator Global Assessment (IGA) score of "moderate" or worse
- In general good health with well-controlled medical problems
- Ability to provide written informed consent and comply with study assessments for the full duration of the study.
- If a female of childbearing potential, a negative pregnancy test and commitment to the use of two forms of effective contraception (birth control) for the duration of the study are necessary.
- If a non-sterile male, commitment to the use of two forms of effective contraception (birth control) for the duration of the study is necessary.
- Normal platelet count
You may not qualify if…
- Patients with known hypersensitivity to efalizumab or any of its components
- Pregnancy or lactation
- Patients receiving immunosuppressive agents
- Prior enrollment in the study
- Participation in another simultaneous medical investigation or trial
- IGA score of "mild," "almost clear" or "clear"
- Systemic therapy for atopic dermatitis, phototherapy or topical therapy (other than moisturizer) within 1 week
- Medical condition which would make use of efalizumab unsafe; would limit compliance with study requirements; or would limit accurate assessment of efficacy.
- Ongoing, active, serious infection
- History of malignancy (except excised basal or squamous cell carcinoma of the skin)
Where it is running
- UMDNJ Psoriasis Center of Excellence — New Brunswick, New Jersey, United States
Full record on ClinicalTrials.gov
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