Study of Adults With Low Growth Hormone Who Survived Childhood Cancer Where Treatment Caused Low Bone Density

Stopped early · Not applicable

Conditions studied: Osteopenia

In brief

The purpose of this project is to evaluate the hypothesis that bisphosphonate treatment given to growth hormone deficient patients (regardless of current growth hormone replacement therapy status and without changing that status) significantly increases total body bone mineral density during an eighteen month period of treatment combined with calcium and Vitamin D when compared to calcium and Vitamin D treatment alone.

Key facts

Study ID

NCT00145704

Run by

State University of New York - Upstate Medical University

People needed

6

Starts

2002-06-01

Expected to finish

2008-10-01

Last updated by the study team

2013-04-08

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Growth hormone deficiency as a complication of treatment for pediatric malignancy
• Dexa (bone densitometry)with z-scores of < -1.0 in at least one site

You may not qualify if…

• Dexa (bone densitometry)with z-scores < -1.0 in at least one site
• Subjects <18 years old
• Pregnant or lactating patients
• Any contraindication for or unwillingness to consider bisphosphonate treatment
• Inability or unwillingness to undergo bone density evaluation
• Other correctable causes of decreased bone mineral density

Where it is running

• Upstate Medical University — Syracuse, New York, United States

Full record on ClinicalTrials.gov

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