Improving Antibiotic Use in Acute Care Treatment
Completed · Not applicable
Conditions studied: Respiratory Infections
In brief
Purpose The emergence and rapid rise in antibiotic resistance among common bacteria are adversely affecting the clinical course and health care costs of community-acquired infections. Because antibiotic resistance rates are strongly correlated with antibiotic use patterns, multiple organizations have declared reductions in unnecessary antibiotic use to be critical components of efforts to combat antibiotic resistance. Among humans, the vast majority of unnecessary antibiotic prescriptions are used to treat acute respiratory tract infections (ARIs) that have a viral etiology. Although the rate of antibiotic prescribing for ARIs by office-based physicians in the US has decreased about 16% from its peak in 1997, the rate of antibiotic prescribing in acute care settings (eg, emergency departments and urgent care centers), which account for 1 in 5 ambulatory antibiotic prescriptions in the US, has shown only a modest decline (6%) during this period. Translation of lessons from intervention studies in office-based practices is needed to improve antibiotic use in acute care settings.
Key facts
- Study ID
- NCT00144040
- Run by
- US Department of Veterans Affairs
- People needed
- 1000
- Starts
- 2004-02-01
- Expected to finish
- 2007-07-01
- Last updated by the study team
- 2015-04-07
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Emergency room patient
- Selected VA or Non-VA patients
- Age 18 years or older
- Patient must have acute respiratory illness
- Patient must not have been seen in Emergency Department within 4 weeks
You may not qualify if…
- Patients less than 18 years of age
- Patient in Emergency Department for non-acute respiratory infection
Where it is running
- VA San Diego Healthcare System, San Diego, CA — San Diego, California, United States
- Charlie Norwood VA Medical Center, Augusta, GA — Augusta, Georgia, United States
- Edward Hines Jr. VA Hospital, Hines, IL — Hines, Illinois, United States
- Kansas City VA Medical Center, Kansas City, MO — Kansas City, Missouri, United States
- New Mexico VA Health Care System, Albuquerque, NM — Albuquerque, New Mexico, United States
- James J. Peters VA Medical Center, Bronx, NY — The Bronx, New York, United States
- Philadelphia VA Medical Center, Philadelphia, PA — Philadelphia, Pennsylvania, United States
- VA Pittsburgh Healthcare System University Drive Division, Pittsburgh, PA — Pittsburgh, Pennsylvania, United States
- South Texas Health Care System, San Antonio, TX — San Antonio, Texas, United States
Full record on ClinicalTrials.gov
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