Immunologic Memory (Supp. of ATN 024)

Completed · Phase 4

Conditions studied: HIV Infections

In brief

This is an exploratory, laboratory-based evaluation of cellular immune response to immunization with hepatitis B surface antigen in HIV-infected and HIV-uninfected adolescents. This is a substudy of ATN 024 and ATN 025. This substudy will compare cellular immune response in responders and nonresponders to immunization and also evaluate the relationship of these factors to the persistence of known correlates of serologic protection for the hepatitis B virus.

Key facts

Study ID

NCT00142753

Run by

University of North Carolina, Chapel Hill

People needed

95

Starts

2005-08-01

Expected to finish

2007-11-01

Last updated by the study team

2017-02-28

Who can join

Age: 12 and older, up to 25. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Subjects that are eligible for participation in ATN 024 and ATN 025 are eligible for ATN 048. Subjects consented for ATN 024 or ATN 025 should be consented for ATN 048 at the same time. A written informed assent/consent must be obtained from the subject along with written parental/legal guardian permission as determined by the local IRB before any study-related procedures are performed.

Where it is running

• Childrens Hosp of Los Angeles — Los Angeles, California, United States
• University of California at San Francisco — San Franciso, California, United States
• Children's Hosp Natinal Med Center — Washington D.C., District of Columbia, United States
• Tulane Med Center — New Orleans, Louisiana, United States

Full record on ClinicalTrials.gov

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