Study Evaluating ERB-041 With Methotrexate in Rheumatoid Arthritis

Completed · Phase 2 · Has a placebo group

Conditions studied: Rheumatoid Arthritis

In brief

The primary objective of this study is to compare the efficacy and safety of 3 dose levels of oral ERB-041 administered daily for 12 weeks versus placebo in subjects with active rheumatoid arthritis who have had a suboptimal response to therapy with stable doses of methotrexate (MTX).

Key facts

Study ID

NCT00141830

Run by

Wyeth is now a wholly owned subsidiary of Pfizer

People needed

159

Starts

2005-08-01

Expected to finish

2006-10-19

Last updated by the study team

2020-09-29

Who can join

Age: 18 and older, up to 80. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Clinical diagnosis of active rheumatoid arthritis for at least 6 months and on a stable dose of methotrexate for at least 12 weeks
• Rheumatoid arthritis onset after 16 years of age

You may not qualify if…

• Any significant health problem other than rheumatoid arthritis
• History of male or female reproductive system cancer
• Clinically significant laboratory abnormalities

Where it is running

• Study site — Largo, Florida, United States
• Study site — Palm Harbor, Florida, United States
• Study site — Sarasota, Florida, United States
• Study site — Boise, Idaho, United States
• Study site — Kansas City, Kansas, United States
• Study site — Frederick, Maryland, United States
• Study site — Albuquerque, New Mexico, United States
• Study site — Charlotte, North Carolina, United States
• Study site — Duncansville, Pennsylvania, United States
• Study site — Austin, Texas, United States
• Study site — Dallas, Texas, United States
• Study site — San Antonio, Texas, United States
• Study site — Spokane, Washington, United States
• Study site — La Crosse, Wisconsin, United States
• Study site — Penticton, British Columbia, Canada
• Study site — Newmarket, Ontario, Canada
• Study site — Toronto, Ontario, Canada
• Study site — Montreal, Quebec, Canada
• Study site — Trois-Rivières, Quebec, Canada
• Study site — Saskatoon, Saskatchewan, Canada
• Study site — Québec, Canada
• Study site — Békéscsaba, Hungary
• Study site — Budapest, Hungary
• Study site — Veszprém, Hungary
• Study site — Brescia, Italy

Full record on ClinicalTrials.gov

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