Study Evaluating GAP-486 on Heart Rhythm in Patients With Coronary Artery Disease

Stopped early · Phase 2

Conditions studied: Arrhythmia

In brief

The purpose of this study is to learn the effects of a test drug on heart rhythms, which may become life-threatening if left untreated, and to provide data to see if the drug is well tolerated and safe.

Key facts

Study ID

NCT00137332

Run by

Wyeth is now a wholly owned subsidiary of Pfizer

People needed

90

Starts

2005-11-01

Expected to finish

2006-10-01

Last updated by the study team

2007-12-10

Who can join

Age: 18 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Patients with or without ICDs (implantable cardioverter defibrillators)
• Patients undergoing an electrophysiology study for evaluation of ventricular rhythm
• Patients with a history of heart disease

You may not qualify if…

• Patients with uncontrolled blood pressure
• Patients with certain cardiac risk factors
• Patients with significant kidney or liver problems

Where it is running

• Study site — Sacramento, California, United States
• Study site — San Francisco, California, United States
• Study site — Washington D.C., District of Columbia, United States
• Study site — Orlando, Florida, United States
• Study site — Peoria, Illinois, United States
• Study site — Iowa City, Iowa, United States
• Study site — Worcester, Massachusetts, United States
• Study site — Ann Arbor, Michigan, United States
• Study site — Lansing, Michigan, United States
• Study site — Southfield, Michigan, United States
• Study site — Minneapolis, Minnesota, United States
• Study site — Newark, New Jersey, United States
• Study site — Winston-Salem, North Carolina, United States
• Study site — Cleveland, Ohio, United States
• Study site — Cleveland, Ohio, United States
• Study site — Hershey, Pennsylvania, United States
• Study site — Wynnewood, Pennsylvania, United States
• Study site — Falls Church, Virginia, United States
• Study site — Norfolk, Virginia, United States
• Study site — Edmonton, Alberta, Canada
• Study site — Vancouver, British Columbia, Canada
• Study site — Victoria, British Columbia, Canada
• Study site — St-Johnâ S, Newfoundland and Labrador, Canada
• Study site — Halifax, Nova Scotia, Canada
• Study site — London, Ontario, Canada

Full record on ClinicalTrials.gov

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