Effect of Smoking Exposure on Smoking Relapse Following Brief Abstinence - 2
Completed · Not applicable
Conditions studied: Tobacco Use Disorder
In brief
Recent research on the effects of nicotine on the brain and behavior presents an opportunity to advance medication development. The purpose of this study is to develop a laboratory model for early-stage testing of new and existing treatments for nicotine addiction. Specifically, the investigators will develop a laboratory model of relapse to cigarette use in nicotine dependent volunteers.
Key facts
- Study ID
- NCT00136838
- Run by
- New York State Psychiatric Institute
- People needed
- 12
- Starts
- 2001-10-01
- Expected to finish
- 2006-06-01
- Last updated by the study team
- 2018-06-18
Who can join
Age: 21 and older, up to 45. Sex: any. Healthy volunteers: not accepted.
You may qualify if…
- Diagnosis of nicotine dependence with psychological dependence
- Smokes at least 15 cigarettes per day for the three months prior to enrollment
- Currently not seeking treatment for nicotine dependence
- Medically healthy, on the basis of physical examination and medical history, vital signs, EKG, and laboratory tests
- Females must use an effective method of contraception for the duration of the study
You may not qualify if…
- Diagnosis of abuse or dependence on alcohol or drugs other than nicotine
- Current Axis I diagnosis or current treatment with psychotropic medications within the 3 months prior to enrollment
- History of schizophrenia or other psychotic disorders, bipolar disorder, or anxiety disorders
- Currently seeking treatment for nicotine disorders
- On parole or probation
- History of seizures or head trauma with loss of consciousness, brain contusion, or fracture
- History of significant recent violent behavior
- Blood pressure greater than 150/90
- History of eating disorders
- Pregnant
Where it is running
- Columbia University — New York, New York, United States
Full record on ClinicalTrials.gov
Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.