Comparing Paroxetine and Duloxetine on Cardiovascular Measures

Completed · Phase 2/Phase 3

Conditions studied: Depressive Symptoms

In brief

This double-blind placebo-controlled trial is designed to test and to compare the cardiovascular profile of paroxetine controlled release (CR) with duloxetine in outpatients with depressive symptoms.

Key facts

Study ID

NCT00136383

Run by

Duke University

People needed

40

Starts

2005-03-01

Expected to finish

2007-06-01

Last updated by the study team

2014-07-21

Who can join

Age: 20 and older, up to 60. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Depressive symptoms
• Ages 20-60
• In good medical health and not pregnant

You may not qualify if…

• Bipolar disorder
• Schizophrenia or other psychotic disorder
• Alcohol or other substance abuse within the last 3 months
• Cognitive impairment
• History of attempted suicide in the past 2 months and who score 4 or more on the suicide item of the MADRS

Where it is running

• Duke University Medical Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

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