Blockade Efficacy of Buprenorphine/Naloxone For Opioid Dependence

Completed · Not applicable

Conditions studied: Opioid-Related Disorders

In brief

Buprenorphine, a treatment for opioid dependence, can be mixed with naloxone, to limit abuse potential. The purpose of this study is to examine the effectiveness of buprenorphine/naloxone that is given at less than daily intervals, in order to prevent withdrawal symptoms associated with stopping opioid abuse.

Key facts

Study ID

NCT00134888

Run by

National Institute on Drug Abuse (NIDA)

People needed

8

Starts

2000-12-01

Expected to finish

2002-11-01

Last updated by the study team

2017-01-12

Who can join

Age: 18 and older, up to 55. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Meets diagnostic criteria for opioid dependence
• Qualifies for opioid substitution treatment (e.g., methadone)

You may not qualify if…

• Significant psychiatric or physical disorder

Where it is running

• Johns Hopkins University (BPRU) Bayview Campus — Baltimore, Maryland, United States

Full record on ClinicalTrials.gov

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