Pediatric Atorvastatin in Diabetes Intervention Trial (PADIT)

Completed · Not applicable

Conditions studied: Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus

In brief

The purpose of this study is to determine if Atorvastatin can improve blood vessel stiffness and blood vessel function in children 10-18 years old with Type 1 and Type 2 diabetes. Subjects will receive atorvastatin 20mg or placebo daily for 3 months and will then switch therapies for the next 3 months. Hypothesis: Atorvastatin will improve blood vessel function by decreasing arterial stiffness and improving blood flow.

Key facts

Study ID

NCT00130481

Run by

University of Florida

People needed

100

Starts

2005-04-01

Expected to finish

2007-04-01

Last updated by the study team

2012-03-07

Who can join

Age: 10 and older, up to 18. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Type 1 Diabetes Mellitus (T1DM) or Type 2 Diabetes Mellitus (T2DM) for more than 1 year
• Age 10-18 years.

You may not qualify if…

• Cardiovascular disease (CVD)
• Liver disease
• Pregnancy
• Use of cholesterol or triglyceride lowering drugs
• Perceived inability to comply with the study protocol
• Endocrinopathy other than diabetes

Where it is running

• University of Florida — Gainesville, Florida, United States

Full record on ClinicalTrials.gov

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