Study of Oral Fampridine-SR in Multiple Sclerosis

Completed · Phase 3 · Has a placebo group

Conditions studied: Multiple Sclerosis

In brief

To assess the safety and efficacy of 10 milligram (mg) twice a day (b.i.d.) Fampridine-SR in patients diagnosed with multiple sclerosis (MS), in a double-blind, placebo-controlled, parallel group study.

Key facts

Study ID

NCT00127530

Run by

Acorda Therapeutics

People needed

300

Starts

2005-05-01

Expected to finish

2006-09-01

Last updated by the study team

2018-09-11

Who can join

Age: 18 and older, up to 70. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• Have a confirmed diagnosis of multiple sclerosis
• Are able to walk with or without an assistive device

You may not qualify if…

• Pregnancy, breastfeeding or females of childbearing potential not using adequate birth control
• Participating in other investigational drug trials
• A medical history or clinical findings that preclude entry into the study
• A medication history that precludes entry into the study
• Previously treated with 4-aminopyridine (4-AP)

Where it is running

• University of Alabama — Birmingham, Alabama, United States
• Barrow Neurology Clinic, St. Joseph's Hospital and Medical Center — Phoenix, Arizona, United States
• USC, Keck School of Medicine — Los Angeles, California, United States
• UC Davis — Sacramento, California, United States
• University of Colorado Health Sciences Center — Denver, Colorado, United States
• Multiple Sclerosis Treatment Center — Derby, Connecticut, United States
• Shepard Center — Atlanta, Georgia, United States
• University of Chicago — Chicago, Illinois, United States
• Indiana University MS Center — Indianapolis, Indiana, United States
• Maryland Center for MS — Baltimore, Maryland, United States
• Wayne State University, Department of Neurology — Detroit, Michigan, United States
• The Schapiro Center for MS — Golden Valley, Minnesota, United States
• Washington University SOM — St Louis, Missouri, United States
• Gimbel MS Center at Holy Name Hospital — Teaneck, New Jersey, United States
• University of Mexico, MIND Imaging Center — Albuquerque, New Mexico, United States
• Maimonides Medical Center — Brooklyn, New York, United States
• Corinne Goldsmith Dickinson Center for MS — New York, New York, United States
• University of Rochester — Rochester, New York, United States
• SUNY - Stony Brook — Stony Brook, New York, United States
• Carolinas Healthcare System — Charlotte, North Carolina, United States
• Cleveland Clinical Foundation — Cleveland, Ohio, United States
• Ohio State University MS Center — Columbus, Ohio, United States
• Oregon Health & Science University, MS Center of Oregon, UHS-42 — Portland, Oregon, United States
• Thomas Jefferson University Physicians — Philadelphia, Pennsylvania, United States
• Allegheny General Hospital, Allegheny Neurological Associates — Pittsburgh, Pennsylvania, United States

Full record on ClinicalTrials.gov

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