Conservative Versus Liberal Red Cell Transfusion in Myocardial Infarction Trial: The CRIT Pilot

Completed · Phase 4

Conditions studied: Myocardial Infarction, Anemia

In brief

The purpose of this trial is to determine whether a conservative or a liberal blood transfusion strategy is better for patients with a heart attack and a low blood count.

Key facts

Study ID

NCT00126334

Run by

Medstar Health Research Institute

People needed

45

Starts

2003-04-01

Expected to finish

2011-01-01

Last updated by the study team

2011-07-21

Who can join

Age: 21 and older. Sex: any. Healthy volunteers: not accepted.

You may qualify if…

• All of the following must be present:
• Acute myocardial infarction with presentation within 72 hours of randomization (acute myocardial infarction is defined as ischemic-type chest discomfort lasting at least 30 minutes associated with creatinine kinase MB (CKMB) or troponin >upper limit of normal [ULN])
• Admission to CCU
• Hematocrit .30 or less
• Written, informed consent

You may not qualify if…

• Inability or unwillingness to receive red cell transfusions
• Active bleeding (overt blood loss accompanied by a decrease in hematocrit of at least 5% in the preceding 12 hours)
• Receipt of red cell transfusion within 7 days of randomization
• Prior severe transfusion reaction
• Pregnancy
• Imminent death
• Decision to provide limited care
• Age <21
• Participation in another clinical trial in which blood transfusion is a requirement or a component of a primary or secondary endpoint
• Previous participation in the CRIT Pilot

Where it is running

• Washington Hospital Center — Washington D.C., District of Columbia, United States
• Washington VA Medical Center — Washington D.C., District of Columbia, United States
• Durham VA Medical Center — Durham, North Carolina, United States

Full record on ClinicalTrials.gov

Trial information comes from ClinicalTrials.gov and is refreshed daily. TrialsForMe does not provide medical care and does not run the studies it lists.