S0417 Bortezomib, Thalidomide, and Dexamethasone in Treating Patients With Relapsed or Refractory Multiple Myeloma

Stopped early · Phase 2

Conditions studied: Multiple Myeloma

In brief

RATIONALE: Bortezomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth. Biological therapies, such as thalidomide, may stimulate the immune system in different ways and stop cancer cells from growing. It may also stop the growth of cancer by blocking blood flow to the cancer. Drugs used in chemotherapy, such as dexamethasone, work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving bortezomib together with thalidomide and dexamethasone may kill more cancer cells. PURPOSE: This phase II trial is studying how well giving bortezomib together with thalidomide and dexamethasone works in treating patients with relapsed or refractory multiple myeloma.

Key facts

Study ID

NCT00124579

Run by

SWOG Cancer Research Network

People needed

7

Starts

2005-08-01

Expected to finish

2010-06-01

Last updated by the study team

2018-08-09

Who can join

Age: 18 and older, up to 120. Sex: any. Healthy volunteers: not accepted.

Where it is running

• Saint Anthony's Hospital at Saint Anthony's Health Center — Alton, Illinois, United States
• Good Samaritan Regional Health Center — Mount Vernon, Illinois, United States
• Hematology Oncology Consultants - Naperville — Naperville, Illinois, United States
• Regional Cancer Center at Memorial Medical Center — Springfield, Illinois, United States
• St. Francis Hospital and Health Centers - Beech Grove Campus — Beech Grove, Indiana, United States
• Reid Hospital & Health Care Services, Incorporated — Richmond, Indiana, United States
• Genesis Regional Cancer Center at Genesis Medical Center — Davenport, Iowa, United States
• Genesis Medical Center - West Campus — Davenport, Iowa, United States
• Tammy Walker Cancer Center at Salina Regional Health Center — Salina, Kansas, United States
• Wesley Medical Center — Wichita, Kansas, United States
• Saint Joseph Mercy Cancer Center — Ann Arbor, Michigan, United States
• CCOP - Michigan Cancer Research Consortium — Ann Arbor, Michigan, United States
• Battle Creek Health System Cancer Care Center — Battle Creek, Michigan, United States
• Mecosta County Medical Center — Big Rapids, Michigan, United States
• Oakwood Cancer Center at Oakwood Hospital and Medical Center — Dearborn, Michigan, United States
• Genesys Hurley Cancer Institute — Flint, Michigan, United States
• Hurley Medical Center — Flint, Michigan, United States
• CCOP - Grand Rapids — Grand Rapids, Michigan, United States
• Lacks Cancer Center at Saint Mary's Health Care — Grand Rapids, Michigan, United States
• Spectrum Health Hospital - Butterworth Campus — Grand Rapids, Michigan, United States
• Metro Health Hospital — Grand Rapids, Michigan, United States
• Van Elslander Cancer Center at St. John Hospital and Medical Center — Grosse Pointe Woods, Michigan, United States
• Holland Community Hospital — Holland, Michigan, United States
• Foote Hospital — Jackson, Michigan, United States
• Arkansas Cancer Research Center at University of Arkansas for Medical Sciences — Little Rock, Arkansas, United States

Full record on ClinicalTrials.gov

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