Effects of Vitamin B12 on the Body's Internal Clock

Completed · Not applicable

Conditions studied: Sleep Disorders, Circadian Rhythm

In brief

Circadian rhythms are 24-hour cycles that influence natural functions in the body such as heart rate, blood pressure, and body temperature. Circadian rhythms provide the body with an internal clock and affect sleep patterns. The purpose of this study is to determine the effects of vitamin B12 supplements on circadian rhythms and sleep-wake regulation.

Key facts

Study ID

NCT00120484

Run by

Brigham and Women's Hospital

People needed

10

Starts

2005-04-01

Expected to finish

2008-01-01

Last updated by the study team

2010-01-14

Who can join

Age: 18 and older, up to 30. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• Diagnosis of delayed sleep phase syndrome OR self-described as a "night owl"

You may not qualify if…

• History of medical illness
• History of psychiatric illness in participant or his or her family members
• Current medication or vitamin use
• Follow a vegan diet
• Significant visual problem
• Recent travel across time zones
• History of rotating shiftwork

Where it is running

• Brigham and Women's Hospital, Harvard Medical School — Boston, Massachusetts, United States

Full record on ClinicalTrials.gov

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