S0408: Capecitabine, Oxaliplatin, and Bevacizumab in Pts Undergoing Surgery for Liver Mets From Colorectal Cancer
Withdrawn before enrolling · Phase 2
Conditions studied: Colorectal Cancer, Metastatic Cancer
In brief
RATIONALE: Drugs used in chemotherapy, such as capecitabine and oxaliplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing. Monoclonal antibodies, such as bevacizumab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread. Others find tumor cells and help kill them or carry tumor-killing substances to them. Bevacizumab may also stop the growth of tumor cells by blocking blood flow to the tumor. Giving capecitabine and oxaliplatin together with bevacizumab before and after surgery may be an effective treatment for liver metastases. PURPOSE: This phase II trial is studying how well giving capecitabine and oxaliplatin together with bevacizumab works in treating patients who are undergoing surgery for liver metastases due to colorectal cancer.
Key facts
- Study ID
- NCT00118105
- Run by
- SWOG Cancer Research Network
- People needed
- 0
- Starts
- 2006-11-01
- Expected to finish
- 2007-04-01
- Last updated by the study team
- 2013-01-03
Who can join
Age: 18 and older. Sex: any. Healthy volunteers: not accepted.
Where it is running
- USC/Norris Comprehensive Cancer Center and Hospital — Los Angeles, California, United States
- Rush-Copley Cancer Care Center — Aurora, Illinois, United States
- Joliet Oncology-Hematology Associates, Limited - West — Joliet, Illinois, United States
- Carle Cancer Center at Carle Foundation Hospital — Urbana, Illinois, United States
- CCOP - Carle Cancer Center — Urbana, Illinois, United States
- St. Francis Hospital and Health Centers - Beech Grove Campus — Beech Grove, Indiana, United States
- Saint Anthony Memorial Health Centers — Michigan City, Indiana, United States
- Reid Hospital & Health Care Services, Incorporated — Richmond, Indiana, United States
- Tammy Walker Cancer Center at Salina Regional Health Center — Salina, Kansas, United States
- Cancer Research Center at Boston Medical Center — Boston, Massachusetts, United States
- West Michigan Cancer Center — Kalamazoo, Michigan, United States
- Bronson Methodist Hospital — Kalamazoo, Michigan, United States
- Borgess Medical Center — Kalamazooaa, Michigan, United States
- CCOP - Montana Cancer Consortium — Billings, Montana, United States
- Hematology-Oncology Centers of the Northern Rockies - Billings — Billings, Montana, United States
- Northern Rockies Radiation Oncology Center — Billings, Montana, United States
- St. Vincent Healthcare — Billings, Montana, United States
- Billings Clinic Cancer Center — Billings, Montana, United States
- Deaconess Billings Clinic - Downtown — Billings, Montana, United States
- Bozeman Deaconess Cancer Center — Bozeman, Montana, United States
- St. James Community Hospital — Butte, Montana, United States
- Frontier Cancer Center — Great Falls, Montana, United States
- Great Falls Clinic — Great Falls, Montana, United States
- St. Peter's Hospital — Helena, Montana, United States
- Glacier Oncology, PLLC — Kalispell, Montana, United States
Full record on ClinicalTrials.gov
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