Nasal Ocular Reflexes Contribute to Eye Symptoms

Completed · Not applicable

Conditions studied: Rhinitis, Allergic, Seasonal

In brief

Eye symptoms of tearing, redness and itching frequently occur in patients with allergic rhinitis or hayfever. The purpose of this trial is to study whether placing an allergen (a substance that causes allergies) directly in your nose can cause you to have eye symptoms as well as nasal symptoms.

Key facts

Study ID

NCT00117832

Run by

University of Chicago

People needed

20

Starts

2005-03-01

Expected to finish

2006-10-01

Last updated by the study team

2013-09-05

Who can join

Age: 18 and older, up to 45. Sex: any. Healthy volunteers: accepted.

You may qualify if…

• History of grass and/or ragweed allergic rhinitis.
• Positive skin test to grass and/or ragweed antigen.
• Positive response to screening nasal challenge.

You may not qualify if…

• Physical signs or symptoms suggestive of renal, hepatic or cardiovascular disease.
• Pregnant or lactating women.
• Upper respiratory infection within 14 days of study start.

Where it is running

• University of Chicago — Chicago, Illinois, United States

Full record on ClinicalTrials.gov

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